thank you
Your email has been sent.
Main Professional Building 541 W Main St 800 - 7,513 SF of Space Available in Lewisville, TX 75057
HIGHLIGHTS
- $18 PSF + NNN (estimated $5.05)
- 2nd-gen medical suites from 1,400 SF to 2,500 SF
- Near historic Old Town Lewisville
- Move-in ready 800 SF former laboratory
- Across from Medical City Lewisville
- 22,914 VPD at W Main & Ray Dunning Blvd
ALL AVAILABLE SPACES(5)
Display Rental Rate as
- SPACE
- SIZE
- TERM
- RENTAL RATE
- SPACE USE
- CONDITION
- AVAILABLE
2nd gen medical space across from Medical City Lewisville 2 exam rooms, 2 offices, reception, lab/nurse station, waiting room, 2 restrooms. Available immediately
- Lease rate does not include utilities, property expenses or building services
1,400 SF available for pharmacy and/or office use.
- Lease rate does not include utilities, property expenses or building services
- Lease rate does not include utilities, property expenses or building services
2nd gen medical space coming available 8/31/2025. 6 Exam Rooms 1 Treatment/Procedure Room 2 Offices Reception Waiting Room 2 Restrooms
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Medical Space
800 SF former laboratory available
- Lease rate does not include utilities, property expenses or building services
| Space | Size | Term | Rental Rate | Space Use | Condition | Available |
| 1st Floor, Ste 101 | 1,413 SF | 3-5 Years | $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,120 /MO $25,434 /YR | Medical | - | Now |
| 1st Floor, Ste 140 G/H | 1,400 SF | 3-5 Years | $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,100 /MO $25,200 /YR | Office/Medical | - | Now |
| 1st Floor, Ste 140B | 1,400 SF | Negotiable | $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,100 /MO $25,200 /YR | Office/Medical | - | August 31, 2025 |
| 1st Floor, Ste 150 | 2,500 SF | Negotiable | $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $3,750 /MO $45,000 /YR | Medical | Full Build-Out | September 01, 2025 |
| 1st Floor, Ste 160 | 800 SF | 3-5 Years | $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $1,200 /MO $14,400 /YR | Office/Medical | - | Now |
1st Floor, Ste 101
| Size |
| 1,413 SF |
| Term |
| 3-5 Years |
| Rental Rate |
| $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,120 /MO $25,434 /YR |
| Space Use |
| Medical |
| Condition |
| - |
| Available |
| Now |
1st Floor, Ste 140 G/H
| Size |
| 1,400 SF |
| Term |
| 3-5 Years |
| Rental Rate |
| $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,100 /MO $25,200 /YR |
| Space Use |
| Office/Medical |
| Condition |
| - |
| Available |
| Now |
1st Floor, Ste 140B
| Size |
| 1,400 SF |
| Term |
| Negotiable |
| Rental Rate |
| $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $2,100 /MO $25,200 /YR |
| Space Use |
| Office/Medical |
| Condition |
| - |
| Available |
| August 31, 2025 |
1st Floor, Ste 150
| Size |
| 2,500 SF |
| Term |
| Negotiable |
| Rental Rate |
| $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $3,750 /MO $45,000 /YR |
| Space Use |
| Medical |
| Condition |
| Full Build-Out |
| Available |
| September 01, 2025 |
1st Floor, Ste 160
| Size |
| 800 SF |
| Term |
| 3-5 Years |
| Rental Rate |
| $18.00 /SF/YR $1.50 /SF/MO $193.75 /m²/YR $16.15 /m²/MO $1,200 /MO $14,400 /YR |
| Space Use |
| Office/Medical |
| Condition |
| - |
| Available |
| Now |
1st Floor, Ste 101
| Size | 1,413 SF |
| Term | 3-5 Years |
| Rental Rate | $18.00 /SF/YR |
| Space Use | Medical |
| Condition | - |
| Available | Now |
2nd gen medical space across from Medical City Lewisville 2 exam rooms, 2 offices, reception, lab/nurse station, waiting room, 2 restrooms. Available immediately
- Lease rate does not include utilities, property expenses or building services
1st Floor, Ste 140 G/H
| Size | 1,400 SF |
| Term | 3-5 Years |
| Rental Rate | $18.00 /SF/YR |
| Space Use | Office/Medical |
| Condition | - |
| Available | Now |
1,400 SF available for pharmacy and/or office use.
- Lease rate does not include utilities, property expenses or building services
1st Floor, Ste 140B
| Size | 1,400 SF |
| Term | Negotiable |
| Rental Rate | $18.00 /SF/YR |
| Space Use | Office/Medical |
| Condition | - |
| Available | August 31, 2025 |
- Lease rate does not include utilities, property expenses or building services
1st Floor, Ste 150
| Size | 2,500 SF |
| Term | Negotiable |
| Rental Rate | $18.00 /SF/YR |
| Space Use | Medical |
| Condition | Full Build-Out |
| Available | September 01, 2025 |
2nd gen medical space coming available 8/31/2025. 6 Exam Rooms 1 Treatment/Procedure Room 2 Offices Reception Waiting Room 2 Restrooms
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Medical Space
1st Floor, Ste 160
| Size | 800 SF |
| Term | 3-5 Years |
| Rental Rate | $18.00 /SF/YR |
| Space Use | Office/Medical |
| Condition | - |
| Available | Now |
800 SF former laboratory available
- Lease rate does not include utilities, property expenses or building services
PROPERTY OVERVIEW
Now available for lease, this well-located medical office opportunity in the heart of Lewisville offers a range of ready-to-occupy medical suites ideal for pharmacy, lab, and general healthcare practices. Situated directly across from Medical City Lewisville and just minutes from historic Old Town Lewisville, this property benefits from excellent visibility and access along W Main Street. With flexible suite sizes ranging from 800 SF to 2,500 SF, and competitive lease terms, this location provides both affordability and immediate usability for growing healthcare operations.
PROPERTY FACTS
Presented by
Main Professional Building | 541 W Main St
Hmm, there seems to have been an error sending your message. Please try again.
Thanks! Your message was sent.